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SUBUTEX (buprenorphine) sublingual tablet is an uncoated oval white flat beveled-edged tablet, debossed with an alphanumeric word identifying the product and strength on one side. subutex pill, It contains buprenorphine HCl, a partial agonist at the mu-opioid receptor, and is available in two dosage strengths, 2 mg buprenorphine and 8 mg buprenorphine (as the free base, equivalent to 2.16 mg buprenorphine hydrochloride USP and 8.64 mg buprenorphine hydrochloride USP). subutex doctors near me, Each tablet also contains lactose, mannitol, cornstarch, povidone K30, citric acid, sodium citrate and magnesium stearate.
Chemically, buprenorphine HCl is (2S)-2-[17-Cyclopropylmethyl-4,5α-epoxy-3-hydroxy-6-methoxy6α,14-ethano-14α-morphinan-7α-yl]-3,3-dimethylbutan-2-ol hydrochloride
Generic Name: buprenorphine (byoo-pre-NOR-feen) Brand Name: Subutex is used for: Treating opioid dependence. subutex vs suboxone, It should be used as part of a complete narcotic dependence treatment plan. subutex 8mg, It may also be used for other conditions as determined by your doctor. Subutex is an opioid (narcotic)
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WHAT IS SUBUTEX SUBLINGUAL?
Subutex is an opioid medication, sometimes called a narcotic.
Subutex oral (sublingual, given under the tongue) is used to treat opioid addiction.
Subutex sublingual may also be used for purposes not listed in this medication guide.
USES OF SUBUTEX DRUG
Subutex is used in the treatment of chronic pain; opiate dependence and belongs to the drug class narcotic analgesics. subutex withdrawal, Risk cannot be ruled out during pregnancy. Subutex 2 mg is classified as a Schedule 3 controlled substance under the Controlled Substance Act (CSA).
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Subutex sublingual tablets are not for use as a pain medication.
MISUSE OF Subutex CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.
Taking this medicine during pregnancy may cause life-threatening withdrawal symptoms in the newborn.
Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.
SUBUTEX is indicated for the treatment of opioid dependence and is preferred for induction. subutex side effects, SUBUTEX should be used as part of a complete treatment plan to include counseling and psychosocial support.
DOSAGE AND ADMINISTRATION
Drug Addiction Treatment Act
Under the Drug Addiction Treatment Act (DATA) codified at 21 U.S.C. 823(g), prescription use of this product in the treatment of opioid dependence is limited to healthcare providers who meet certain qualifying requirements, orange subutex, and who have notified the Secretary of Health and Human Services (HHS) of their intent to prescribe this product for the treatment of opioid dependence and have been assigned a unique identification number that must be included on every prescription.
Important Dosage And Administration Instructions
SUBUTEX is administered sublingually as a single daily dose.
SUBUTEX does not contain naloxone and is preferred for use only during induction. subutex clinic near me, Following induction, SUBOXONE sublingual film or SUBOXONE sublingual tablet is preferred due to the presence of naloxone when clinical use includes unsupervised administration. snorting subutex, The use of SUBUTEX for unsupervised administration should be limited to those patients who cannot tolerate SUBOXONE sublingual film or SUBOXONE sublingual tablet; for example, those patients who have been shown to be hypersensitive to naloxone.
Medication should be prescribed in consideration of the frequency of visits. subutex doctors, Provision of multiple refills is not advised early in treatment or without appropriate patient follow-up visits.
Prior to induction, consideration should be given to the type of opioid dependence (i.e., long-or short- acting opioid products), the time since last opioid use, and the degree or level of opioid dependence.
Patients Dependent On heroin Or Other Short-Acting Opioid Products
At treatment initiation, the first dose of SUBUTEX should be administered only when objective and clear signs of moderate opioid withdrawal appear, and not less than 4 hours after the patient last used an opioid.
It is recommended that an adequate treatment dose, titrated to clinical effectiveness, should be achieved as rapidly as possible. subutex clinics near me, The dosing on the initial day of treatment may be given in 2 mg to 4 mg increments if preferred. subutex dosage, In some studies, gradual induction over several days led to a high rate of dropout of buprenorphine patients during the induction period.
In a one-month study, patients received 8 mg of SUBUTEX on Day 1 and 16 mg SUBUTEX on Day 2. From Day 3 onward, patients received either SUBOXONE sublingual tablet or SUBUTEX at the same buprenorphine dose as Day 2 based on their assigned treatment. Induction in the studies of buprenorphine solution was accomplished over 3-4 days, depending on the target dose.
Patients Dependent On Methadone Or Other Long-Acting Opioid Products
Patients dependent upon methadone or other long-acting opioid products may be more susceptible to precipitated and prolonged withdrawal during induction than those on short-acting opioid products; therefore, the first dose of SUBUTEX should only be administered when objective and clear signs of moderate opioid withdrawal appear, and generally not less than 24 hours after the patient last used a long-acting opioid product.
There is little controlled experience with the transfer of methadone-maintained patients to buprenorphine. subutex generic, Available evidence suggests that withdrawal signs and symptoms are possible during induction onto buprenorphine. subutex pictures, Withdrawal appears more likely in patients maintained on higher doses of methadone (>30 mg) and when the first buprenorphine dose is administered shortly after the last methadone dose.
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